Naproxen is a widely used anti-inflammatory agent. Only the (S) enantiomer is safe to use, while the (R) enantiomer is reported to be a liver toxin.
a. If the optical rotation [α] of (S)-naproxin is equal to +50.26o what is the optical rotation of the (R) enantiomer?
b. What would you expect the optical rotation to be if there was a 1:1 mixture of enantiomers?
c. What would you expect the optical rotation to be if there was optical purity, or enantiomeric excess, of 23% of the (S)- enantiomer?